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Frequently Asked Questions

What are the potential applications for hypothermia therapy?
There are a number of clinical applications where the induction of mild hypothermia (32 - 33°C) could offer benefit. These clinical applications include:

  • Acute Ischemic Stroke
  • Acute Myocardial Infarction (AMI)
  • Post Cardiac Arrest
  • Cerebral Aneurysm and Bypass Surgeries
  • Head Injury

General temperature management (fever control) offers additional opportunities for endovascular-based technologies. General temperature management involves achieving and maintaining normothermic (37°C) temperatures by warming or cooling patients. Clinical applications include:

  • Neurological Intensive Care
  • Cardiovascular Surgery
  • General Surgery
  • Trauma Surgery

What are the benefits of endovascular cooling?

  • Endovascular cooling allows the clinician to directly cool the patient's core body which provides an increased rate of thermal energy transfer and greater temperature control.
  • Cooling can be accomplished in awake patients. By cooling the core body directly, skin can be warmed to provide patient comfort and reduce the shivering threshold.

Why is INNERCOOL's Celsius Control System™ technology beneficial?

  • The Celsius Control™ Catheter's flexible Temperature Control Element (TCE) enhances thermal management and heat exchange within the core body to deliver controlled cooling and/or warming. Clinical experience with the Celsius Control System has shown average cool down rates of 4.5 - 5.0°C/hr, target temperature control of ± 0.1°C and average rewarm rates of 2.0 - 3.0°C/hr.
  • The Celsius Control Catheter can be placed into the inferior vena cava using standard catheter insertion techniques.
  • The Celsius Control Console combines user-friendly interface capabilities with control algorithms that allow precise achievement and maintenance of target temperature.
  • The Celsius Control System does not infuse fluid into the patient, nor is blood circulated outside of the body.

1Merchant et al ãTherapeutic Hypothermia after Cardiac Arrest: Unintentional Cooling is Common Using Ice Packs and Conventional Cooling Blanketsä Critical Care Medicine 2006, Vol. 34, No. 12.