INNERCOOL therapies, Inc.

InnerCool Therapies is a medical technology company leading the field of Temperature Modulation Therapy (TMT), which is the practice of altering body temperature to preserve tissue and improve patient outcomes. A growing base of clinical research shows the rapid induction of mild hypothermia (33°C - 34°C) during periods of ischemia can protect tissue from ischemic damage. Furthermore, recent studies have shown that the earlier cooling is achieved in the setting of ischemia and reperfusion, the better the outcome.1,2,3

InnerCool currently offers clinicians the first complete continuum of Temperature Modulation Therapy products from endovascular catheters which rapidly cool and gradually or rapidly re-warm patients, to an innovative surface-based cooling and warming system, providing unsurpassed flexibility for treating a range of patients with complex needs.

InnerCool's RapidBlue™ system for high-performance endovascular temperature modulation includes a programmable console with an enhanced user interface and a catheter designed to quickly modulate patient temperature.

InnerCool's CoolBlue™ surface-based temperature modulation system includes a console and a disposable CoolBlue vest with upper thigh pads, is designed for use in less acute patients, or in clinical settings best suited to prolonged temperature management.

InnerCool is leading the field in applying temperature modulation therapy to specific regions of the body to protect tissue and organs during surgical procedures.


References
  1. Abella, B et al. "Intra-Arrest Cooling Improves Outcomes in a Murine Cardiac Arrest Model", Circulation. June 8, 2004. pg 2790.
  2. Nozari, A. et al "Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation" Circulation. 2006 Jun 13; 113(23):2690-6.
  3. Tanimoto, H et al "Rapidly Induced Hypothermia with extracorporeal lung and heart assist improves the neurological outcome after prolonged cardiac arrest in dogs" Resuscitation 2006 Nov 9. PMID: 17097794.